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Cognitive Strategy Reduces Craving by Altering Brain Activity

Brain imaging reveals changes when smokers focus on long-term consequences of their tobacco use.April 19, 2012Lori Whitten, NIDA Notes Staff WriterAddiction makes it difficult for people to look beyond...

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Well-Known Mechanism Underlies Benzodiazepines' Addictive Properties

Like opioids and cannabinoids, diazepam and other benzodiazepines take the brakes off activity of dopamine-producing neurons.April 19, 2012By NIDA Notes StaffSince their introduction in the 1960s,...

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Physical Activity Reduces Return to Cocaine Seeking in Animal Tests

Exercise also decreases neural change linked with drug seeking during abstinence.April 19, 2012By Lori Whitten, NIDA Notes Staff WriterAerobic exercise might help cocaine abusers establish and maintain...

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Home Visits by Nurses to Low-Income First-Time Mothers Yield Enduring Benefits

Savings on welfare-related outlays offset the cost of a program that improved childrenApril 19, 2012By Lori Whitten, NIDA Notes Staff WriterHome visits by nurses to low-income first-time mothers,...

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Buprenorphine During Pregnancy Reduces Neonate Distress

A multisite clinical trial lays groundwork for improving care for mothers and babies affected by opioid dependence.July 06, 2012Lori Whitten, NIDA Notes Staff WriterA NIDA-supported clinical trial, the...

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Potential Pain Medication Targets Peripheral Nerves

Compound may relieve chronic pain without CNS side effectsSeptember 17, 2012NIDA Notes StaffOxycodone, hydrocodone, morphine, and other opioids are the most effective analgesic medications currently...

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Animal Research Advances Effort to Develop Vaccines Against Cocaine, Heroin...

To block the effects of abused drugs, scientists recruit the immune system.September 17, 2012Lori Whitten, NIDA Notes Staff WriterNIDA-supported vaccine developers have achieved promising preclinical...

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Stress Receptor Mediates Lifelong Consequences of Early Trauma

Overexpression of the glucocorticoid gene in the first weeks after birth increased anxiety and response to cocaine in adulthood.November 29, 2012Sharon Reynolds, NIDA Notes Contributing Writer...

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Brief Intervention Helps Adolescents Curb Substance Use

Two hour-long sessions a week apart reduce symptoms of substance abuse or dependence.January 02, 2013Lori Whitten, NIDA Notes Contributing WriterDrug- and alcohol-involved middle and high school...

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Nicotine Makes Mouse Brain More Responsive to Cocaine

Neurobiological effect may explain why smoking is gateway to cocaine abuse, researchers say.February 20, 2013Lori Whitten, NIDA Notes Staff WriterNicotine sensitizes the mouse brain to the addictive...

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Receptor May Underlie Gender Differences in Response to Smoking Cessation...

May 24, 2013Men benefit more than women from nicotine replacement therapy (NRT) for smoking cessation because nicotine affects a key neuroreceptor differently in the two sexes, a NIDA-sponsored study...

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Problem Behaviors Can Signal Risk in Prescribing Opioids to Teens

July 18, 2013In the years 2007 to 2009, more than 1 in 5 high school seniors nationwide had used an opioid painkiller (e.g., Vicodin, OxyContin, Percodan, Percocet, Demerol, Dilaudid, morphine, or...

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Well-Known Mechanism Underlies Benzodiazepines' Addictive Properties

Like opioids and cannabinoids, diazepam and other benzodiazepines take the brakes off activity of dopamine-producing neurons.April 19, 2012By NIDA Notes StaffSince their introduction in the 1960s,...

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Problem Behaviors Can Signal Risk in Prescribing Opioids to Teens

July 18, 2013In the years 2007 to 2009, more than 1 in 5 high school seniors nationwide had used an opioid painkiller (e.g., Vicodin, OxyContin, Percodan, Percocet, Demerol, Dilaudid, morphine, or...

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Study Pinpoints Cognitive Deficits Due to Cocaine, Finds Potential for Recovery

July 29, 2013Brittany Moya del Pino, NIDA Notes Contributing WriterA lack of effective medications to treat cocaine addiction means that the current best hope for recovery is behavioral therapy, in...

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Early-Onset, Regular Cannabis Use Is Linked to IQ Decline

August 13, 2013Kathryn Calkins, M.A., NIDA Notes Staff Writer In this video, Dr. Madeline Meier discusses her study of marijuana and IQ.Regular cannabis use that starts in adolescence strips away IQ, a...

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